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Synecta™ T2 CDNP
Synecta T2 is made for easy and robust T cell activation and expansion while providing maximal freedom to add cytokines
Composition
Costimulatory ligands and signals: OKT3 scFV, CD86
- Transduce on Day 0
- Add any soluble or membrane-bound cytokines
- Use any serum-free or serum-containing medium
- Easily adaptable protocols for use with a variety of vessels (e.g., flasks) and bioreactors (e.g., Grex®)
- Finalize drug product formulation without a de-beading step
- Maximize cell yield while avoiding overstimulation by adjusting dose
- Activate PBMC, or either negatively or positively selected T cells
Data
Synecta T2 is easy to use, with high dose-dependent cell yields, and a recommended dose of 30-50 μL of Synecta T2 per 1 million cells. The product is agnostic to the use of media, cell isolation techniques, and bioreactors. We strongly recommend adding lentivirus vectors on Day 0 together with Synecta T2.
Synecta T2 is stored at -80°C long term. Once thawed the product can be refrozen once.
Synecta T2 CDNPs are provided in a crystal AT-Closed Vial® for improved sterility. A vial adapter or syringe can be used to apply or aliquot the product.
The protocol is available upon request.
Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
A lot-specific CoA will be provided with each shipment.
Please contact our Customer Support with any questions.
Safety Data Sheet (SDS)
